The very idea of a “bed” bug is misleading to some. While some bed bug infestations have rendered mattresses unusable after an extreme infestation, it is actually not the place they are mostly likely to be laying in wait. Bed bugs can survive anywhere, but more often than not they will be found in the wooden frame of your bed before making the move towards the mattress.
In fact, most bed bug infestations that come from within a home are from the floor boards of a given room. There, bugs live for extended periods of time before overwhelming you and your home by moving anywhere and everywhere else. The moment that bed bugs begin to spread it can seem like they are everywhere but especially in things that are fabric, like mattresses and clothes. This is merely a product of the fact that these items are closest to us and as a result the first time we notice the infestation.
Of course, you will be hard pressed to get rid of all of the wood in your home. This is one reason why we are all so vulnerable to finding bed bugs in our homes. It is almost comforting in a way.